- Won Broadway's 2001 Tony Award as Best Director (Play) for "Proof." He has also been Tony-nominated four other times as Best Director (Play): in 1989 for "The Heidi Chronicles;" in 1992 for "Conversations with My Father;" in 1993 for "The Sisters Rosensweig;" and in 2002 for a revival of "Morning's at Seven."
- Son of Dorothy Ruth Pirone, who was adopted by Babe Ruth and Helen Woodford Ruth. Cousin of Linda Tosetti.
- Stepfather of Martha Plimpton (now divorced from Plimpton's mother).
- He was awarded the 1990 Drama-Logue Award for Direction for "The Heidi Chronicles" at the Center Theatre Group/Ahmanson at the James A. Doolittle (University of California) Theatre in Los Angeles, California.
- He was awarded the 1993 Drama-Logue Award for Direction for the play, "Conversations with My Father" in presented by the Center Theatre Group/Ahmanson at the James A. Doolittle (University of California) Theatre in Los Angeles, California.
- He was awarded the 1994 Drama-Logue Award for Direction for "The Sisters Rosensweig" in presented by the Center Theatre Group/Ahmanson at the James A. Doolittle (University of California) Theatre in Los Angeles, California.
- He was awarded the 1993 Drama Logue Award for Outstanding Direction for "The Substance of Fire" at the Mark Taper Forum Theatre in Los Angeles, California.
- He was awarded the 1996 Drama Logue Award for Outstanding Direction for "Psychopathia Sexualis" at the Mark Taper Forum Theatre in Los Angeles, California.
- He was awarded the 2004 Los Angeles Stage Alliance Ovation Award for Best Director of a Play for "Intimate Apparel" in association with Roundabout Theatre Company production at the Mark Taper Forum Theatre in Los Angeles, California.
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