Segue una piccola squadra di investigatori riuniti per rintracciare e catturare gli assassini più pericolosi, tutti appena fuggiti da una prigione segreta che non dovrebbe esistere.
Dopo un'esplosione in un carcere di massima sicurezza, un pericoloso assassino evade. L'agente FBI Bex Henderson, caduta in disgrazia, viene richiamata per catturarlo prima che torni a uccidere.
Clayton Jessup, a deranged killer who targets happy families, is on the loose and looking to kill again, sending the team on a manhunt to stop him. Bex learns who she can and can't trust.
In rural Montana, the team hunts down Brenda Lowe, a brutal serial killer obsessed with wolves. Bex and the team must track Lowe through the wilderness, all while dealing with local Rangers out for their own form of vigilante justice.
Dr. Ezekiel Malak, a hospital psychiatrist turned deranged killer, is prowling for new victims in Chicago, so Bex and the team work to find a method to his madness in a desperate bid to get ahead of him.
Arlo Brandt, a hoarder-turned-serial killer, emerges from the Pit with newly found purpose. As Arlo hunts for innocent victims, Bex and the team must get inside a deranged mind.
When Bex and the team race to stop Roy Barber, known as the Couple Killer, before he strikes again, they uncover a chilling scheme that puts Roy's crimes in an entirely new light.
Bex and the team race to catch Mark Marsden, known as the Widower, a handsome and charming serial killer who murdered three of his wives in cold blood. Everything changes when Mark decides to take a new bride.
The student becomes the master, when an escaped serial killer from the Pit decides to adopt another inmate's style of killing as a way of paying homage to them.
Bex and the team track the brilliant and beguiling Jenna Wells, the notorious Killer Chemist, whose therapy in the Pit has made her even more dangerous and deranged.
