Marisa Abela had done most of the singing in this film herself. She trained two-and-a-half hours of singing lessons every day for four months in order to mimic Amy Winehouse's vocals.
Scenes were filmed at Ronnie Scott's Jazz Club at 47 Frith Street, Soho, London W1D 4HT, England and outside Amy Winehouse's first flat in Camden Town, and at Primrose Hill, London. In February, scenes were filmed inside the Metropolis Studios in Chiswick, London.
Jeff Tunke claimed he was cast as Mark Ronson and his scenes were deleted. However, director Sam Taylor-Johnson said Ronson was never a character in the film.
Lady Gaga was considered for the role of Amy Winehouse before Marisa Abela was cast. In an interview with The Sun, Lady Gaga admitted that she was often mistaken for the late Amy Winehouse at the beginning of her career in music and bleached her hair blonde in light of that fact.
Following the death of Amy Winehouse on July 23, 2011, several filmmakers attempted to create biopic projects but none of them progressed. By 2022, StudioCanal UK moved forward with production, and filming took place in London from January to April 2023.