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The sheriff is played by David Naughton who was the Werewolf in American Werewolf in London.

Richard Tyson's character's name is Toblat, an anagram of Talbot, the name of Lon Chaney Jr.'s character from The Wolf Man (1941).

The genetics lab that Uncle Charlie sends Toblat's DNA sample to is called NAMFLOW LABORATORIES. Spell NAMFLOW backwards and you get WOLFMAN.

Clint Howard's character is named Fulton Chaney, an obvious accolade to Lon Chaney Jr. who played the original Wolf Man in the 1941 version.

Mitch's cabin was off Fire Road 13. 13 is the universal number signifying evil and bad luck.