The dilapidated area of the hospital in the film was actually an abandoned hospital, and its state (the paint peeling of the walls and everything falling to pieces) is exactly as the filmmakers had found it.
In one scene, Brigitte's leg gets snapped sideways and she has to snap it back into place. Reportedly, Emily Perkins used her own leg in the shot (as opposed to a prop leg).
Despite prominent billing, Katharine Isabelle (Ginger) appears in approx. 3 minutes of screen time.
A lot of the film was shot on location (apart from Ghost's house and the vents), and was the highest budget "Ginger Snaps" film at 4.8 million Canadian dollars.