In the travel agency's window is a sign that reads, "TWA movie-in-flight: Jerry Lewis in 'The Disorderly Orderly'".
The interior was shot with the wood of the Greystones grand staircase painted white to better represent a hospital. It was almost ruined due to the paint not coming off after shooting. It was lead based paint and had to be removed with sand blasting. That same year Bette Davis in "Dead Ringer" utilized the exact same entrance hall with the white paint intact, as did "The Loved One" in 1965.
This, and the previous Jerry Lewis comedy, "The Patsy" (1964), would be the final feature films for Everett Sloane. He would be in high demand for television roles, and for voice work, until his passing the following year.
When Lewis starts picking oatmeal off Freeman, she begins to break up. Jerry ad libs, "Don't cry!" Freeman picked up on this cue and immediately turned it into a soft weeping. Tashlin wisely left it in the picture.
Dr. Howard tells Jerome she doesn't want to sound like Raymond Massey or Sam Jaffe. Like herself, they were chief administrators of hospitals in famous television series at the time, "Dr. KIldare" and "Ben Casey".