Chemistry is a super-feel-good drama about the relationship between a man navigating a complicated personal and professional life, and the attractive manic pixie dream cop who rescues him from a car wreck using mouth to mouth. Lots of sex and nakedness ensue.
One of Cinemax's last attempts at original scripted programming for the After Dark segment, this is last-decade-era late night adult-oriented cable TV schlock and it makes no pretense of being otherwise. The soap opera-like plot developments are silly and none of the characters behave realistically, but everyone is likeable and, while this isn't a straight up comedy, there's a healthy level of self-awareness present - often conveyed in direct fourth wall breaking - and a sense that everyone's doing their earnest best to tell a story with heart and entertain and engage the viewer, even the buddy character with the annoyingly bad fake English accent.
Ana Alexander is a sight and her on-screen chemistry with Jonathan Chase is legit - they're both extremely easy to look at, especially together. It's unfortunate (if completely understandable from a career development standpoint) that she walked away from the series after one season, however, as it seemed like there was still a good bit of story left to tell. To fans of this particular kind of programming it's even more disappointing that she left the genre altogether, but that just makes her work in this series that much more special.
