Anecdotes

Claire Refield, Leon Kennedy, and Ingrid Hunnigan are the only characters that come from the video game series, and voiced by the same actors.

Takes place between the events of Resident Evil 4 (2005) and Resident Evil 5 (2009).

(at around 23 mins) The scene in which Claire and Leon meet, is a reenactment of how they met in Resident Evil 2 (1998). In the game: Leon runs towards the diner and sees Claire being faced off with a zombie. He say's "Get down!" and shoots the zombie. Claire then looks at his face as he offers her his hand. In the movie, Claire goes off to look for a survivor that she hears running around, she looks out the corner of a wall to hear Leon say, "Get down!" He shoots the zombies and offers Claire his hand as she says, "Leon!"

This the first Resident Evil movie to be in CGs (computer graphics), and is also the first Resident Evil to be based directly off the games, and not an original script like the live-action movies were.

At the very end of the movie, before the credits roll, the company Tricell (Umbrella's replacement and merger) is briefly introduced, looking for any remains of the G-Virus. Tricell is more known in the next Resident Evil game, Resident Evil 5 (2009).