Natalya Rudakova, who was a hairdresser with no acting experience prior to this film, was discovered by producer Luc Besson as he was walking down the street in New York. Besson caught up to her and asked her to take some acting lessons and then come in for an audition.
All the car stunts were performed in real time, without models and little to no CGI, which naturally provided its daily dose of challenges to Michel Julienne's stunt team.
Valentina has a Chinese character tattooed on the back of her neck. It is the character for peace.
The car that Frank drives is an Audi A8 a with a six-liter W12 engine. The engine is derived from the Bentley Continental GT. The W12 engine was made by Volkswagen.
Olivier Megaton views the "Transporter" franchise as being somewhere in between the James Bond and "Die Hard" series, with a slight edge to "Die Hard."