When Big Fate shoots Andy, he does so with a pistol drawn with his right hand, after discarding the shotgun. A moment later, Big Fate is shown with the shotgun back in his right hand.
After the shoot out with Big Fate's crew, Dave Jacobs's soul gets shot again. When he falls down from dancing his arm is underneath and behind him, but in the next shot his arm is tucked underneath him out of sight.
When McDonagh searches the couple outside the Gator Retreat, the passenger side view mirror on his car is missing. Later the mirror is there again.
At the beginning right before McDonagh is awarded with the distinguished service cross, he is seen sitting on the far left side. In the next shot, he is sitting second to the far left side.
When McDonagh arrives at the RTA involving the alligator there is a red pick-up truck in between the two lanes of freeway traffic. Then, when he asks Lt. Stoyer to do him a favour, the truck is not there.
Only one of the "iguanas" featured was an iguana. The other lizard was a bearded dragon. The two species are not related and come from opposite sides of the world (iguanids originate in the Americas, whilst the bearded dragon originates in Australasia).
The film is set "six months" after hurricane Katrina, putting the action in the movie occurring sometime around February 2006. In the film, Terence McDonagh continually bets on college football games, though in reality the football season is over by the time the action supposedly takes place.
McDonagh bets several times on college football games featuring Louisiana. The state has several universities with football programs, however there is no Louisiana University. There is a Louisiana State University (LSU) but they are never referred to as simply "Louisiana".
When Big Fate and his crew shoot up the three guys who are after The Lieutenant's money, you can clearly see one of the bodies on the office floor move a finger when the iguana approaches him.
When arriving at the RTA with the alligator a string/wire can be seen moving the animal's leg.
When McDonagh blackmails Renaldo, his jaw movement often does not match his dialogue when the camera films him from behind.
When Lieutenant McDonagh is having sex in the parking lot with the girl, the mic on her back is visible twice.
When Lieutenant McDonagh is driving with the witness to Biloxi he crosses the Mississippi River over the GNO bridge going the wrong direction. The view of the twin smoke stacks indicate he is heading to the west bank of the river. The only non-circuitous route back to the east bank would be via ferry routes that were not restored at that time and run through St Bernard Parish.
For the bet on the "Lousiana"-Texas game, Louisiana is a 6 point favorite and McDonagh is betting ON Louisiana which means he expects them to win by MORE than 6 points, not less. Had he wanted the score to be less than a 6 point spread he would have bet on Texas.
After blackmailing Renaldo Hayes and asking him to shave points in Lousiana's upcoming game with Texas, Terence meets with his bookie and bets on Lousiana - he should have said he was betting on Texas, which did end up being the winning bet.