Just like in Twitches, the twins use magic to switch clothes. As a result someone on a bicycle crashes. In Twitches, a man on a bicycle crashes into a car. In Twitches Too, two men on bikes crash into bushes.
Jennifer Robertson portrayed Ileana in the first film. In the sequel, Ileana's character is played by Leslie Seiler.
Tia plays Alex and Tamera plays Camryn. Just like in the first film, Tia stepped in to play Tamera's part for a small scene when Camryn's party starts. Tamera stepped in to play Alex when Camryn sees Marcus studying with Alex and gets jealous.