Robert Englund was meant to reprise his role as Mayor Buckman, but was kept being re-scheduled due to lack of budget. The filmmakers decided to make the film using the budget they had, and cast Bill Moseley, all without Robert's knowledge.
The film was shot over a period of twelve days on-location in Iowa.
Originally, this film was to have the name "2001 Maniacs: Beverly Hellbillys", but was changed when it was decided that it would be to expensive to film in Beverly Hills, California. If they went this route, the film wouldn't be too different, except prehaps the reality stars wouldn't be travelling.
Because it was shot outside along the Missouri River, mosquitoes became a serious issue, especially at dusk. Sending various Production Assistants out for insect repellent became nearly a nightly ritual.
Ryan Fleming broke his left wrist a week before production, and performed the role of Hucklebilly wearing a removable cast hidden under the sleeve of his shirt, except for the skinny dipping scene, where he removed the cast for each take.