To promote the movie, the studio put a big Eddie Murphy head on a trailer to tour the US.
Eddie Murphy considers Meet Dave as one of the worst movies he ever made: "I even played a spaceship once. That s*** didn't go well".
Paul Scheer was originally cast as Lieutenant Buttocks but was replaced during filming after filming some of his scenes and recast as Lieutenant Kneecap. However, the majority of his role was deleted from the final cut.
During an interview, Scott Caan teased for "Meet Dave 2", but, due to the movie bombing at the box office, a sequel didn't happen.