Jeffrey Tambor filmed his role during a two-day break in the shooting of Hellboy II : Les Légions d'or maudites (2008).
Several of the characters in this movie have alliterative names (Rick Riker, Jill Johnson, Lou Landers, etc.) reflecting Marvel's penchant of giving its characters alliterative names (e.g. Peter Parker, Bruce Banner, Stephen Strange, Bucky Barnes, Sue Storm, Matt Murdoch, Otto Octavius, Pepper Potts).
Michael Papajohn, who plays the mugger who ends up gunning Rick's parents down, originated the role of Carradine - the man who steals Uncle Ben's car after shooting him - in Spider-Man (2002).
This movie was not screened for critics.
Drake Bell's character is mostly based on Spider-Man. A few years after this movie, he voiced Spider-Man in the TV series Ultimate Spider-Man (2012). He also shares the same birthday as Tobey Maguire, who plays the titular Spider-Man in Sam Raimi's trilogy.