The title is a play on words: "Matando Cabos" means "Killing Cabos" Cabos is the last name of one of the characters. But if the "M" is removed it becomes "atando Cabos" that means "Tying lose ends".
Jaque (Tony Dalton) mentions to Mudo (Kristoff) "Being on TV was never my thing". Both Tony Dalton and Kristoff Raczynski once starred on "No te equivoques", a Jackass-like TV show.
Despite playing a couple of Mexican office workers, neither Kristoff Raczynski nor Tony Dalton were born in Mexico, Raczynski were born in Moscow, Russia and Dalton in Laredo, Texas.
According to the movie's writers (Tony Dalton and Kristoff Raczynski) they pitched the script to at least twenty different producers before reaching Fernando and Billy Rovzar, who loved the script and finally greenlighted the project