Arnold Schwarzenegger was inspired to become a bodybuilder because of Reg Park's performance and physique in this film.
Reg Park had to do all of his own stunts, as was common in "sword-and-sandal" movies. There were simply no Italian stuntmen available who were big enough to double for such massive, imposing body builders as Park and his colleagues.
The film started a short-living subgenre of films trying to combine the peplum genre with horror elements. Films considered belonging to this subgenre include Riccardo Freda's The Witch's Curse and Sergio Corbucci's and Giacomo Gentilomo's Maciste contro il vampiro.
The Opera Theater Oregon commissioned composer Patrick Morganelli to write a companion piece to the film, Hercules vs. Vampires, which premiered in Portland in 2010. In April 2015 the work was staged by the Los Angeles Opera.