Rated by many as one of the greatest bouts of all time was his May 7, 2005 10th round knockout victory over Jose Luis Castillo for The World Lightweight Championship. Though Corrales twice came off the canvas to knock Castillo out, in the same round, that result is tempered by the fact that after each knockdown, Corrales, while on his feet, intentionally spit his mouth piece out. On both occasions the referee had to halt the action, however brief, to put Corrales' mouthpiece back in and order points deducted from Corrales' scorecard, giving Corrales additional time to recover before scoring his improbable knockout.
