Brandon Aiyuk est né le 17 mars 1998 en Californie, États-Unis. Il est marié avec Rochelle Searight depuis le 13 avril 2025. Lui et Rochelle Searight ont un enfant.
He is the 2nd Sun Devil Football Player to be drafted in the 1st round of the NFL Draft and the 2nd Sun Devil Wide Receiver to be drafted in the first round since N'Keal Harry was drafted in 2019 by the New England Patriots.
