- She acts, sings and does radio series.
- She did an Etisalat commercial in 2010 and a Pepsi Commercial in 2011.
- Donia is an UNICEF Egypt Ambassador.
- Her parents Samir Ghanem and Dalal Abdel Aziz appeared with her in "Lahfa", "Nelly & Sherihan", "Fi Al La La Land" and "Badal El Hadouta 3".
- She is an UNICEF Egypt Ambassador.
- She performed a song called "Nafs El Horouf" with a disabled kid in a celebration for the International Day of Persons with Disabilities held on December 24, 2018 in the presence of the Egyptian President.
- Reaching 8 million fans on Instagram, Donia became the most followed Egyptian actress & the 5th most followed Egyptian artist as of June 16, 2019.
- Donia hosted the first episode of Saturday Night Live Arabia in February 2016.
- She was #2 in Forbes Middle East Top 10 Arab Female Actors 2017.
- She was #28 in Forbes' Top 100 Arab Celebrities ranking for 2017.
- In 2016, She co-starred in Magdi Yacoub Heart Foundation ad titled: Ersem Alb (Draw a Heart) which included prominent Egyptian artists and footballers. The ad was one of the most viral ads of Ramadan 2016.
- She featured in Google's International Women's Day 2016 doodle, which was visible to users in the Middle East and North Africa.
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