It took Creators Dan Povenmire and Jeff "Swampy" Marsh sixteen years to get this show on television.
Phineas and Ferb is the longest-running Disney animated show, lasting from 2007 to 2015, beating Kim Possible (2002) for five years from 2002 to 2007.
Thomas Brodie-Sangster (Ferb Fletcher) recorded his audio in the U.K. and sent it to the U.S. Because Ferb rarely spoke, his voice actor didn't need to live near production.
Jaret Reddick, lead singer of the band Bowling for Soup, which did the theme song for this show, is the voice of Danny, lead singer of the fictitious band Love Händle in the series.
Director and Creator Dan Povenmire, and Director Zac Moncrief left Les Griffin (1999) to work on this show.