All of Granny's dogs are bulldogs, one of Sylvester's most persistent foes. He would face them again in the 1954 short "Dog Pounded."
Tweety breaks the fourth wall several times here.
The sign on the store next to the pet shop says "I. WYNER CO." -a sneaky self-promotion by background artist Irv Wyner.
The title refers to the 1927 song "Ain't She Sweet" composed by Milton Ager with lyrics by Jack Yellen, which became a Tin Pan Alley standard.
Sylvester's souped up flying machine is a nod to the jet age. The space era was just around the corner, too.