Will Forte wrote the role of Carol specifically for Kristen Schaal.
Patti Forte, Will Forte's real-life mother, played Patti Miller in the premiere episode "Alive in Tucson". Patti Miller was the mother of Phil Miller, and was shown during a flashback on one of Phil's past birthdays. In the show, she was explained to have been killed by the virus.
June 17th is marked on the calendar as Phil Miller's (Will Forte's) birthday, which is Forte's actual birthday.
The main character, Phillip "Tandy" Miller, was named after the Executive Producers of the show, Phil Lord and Christopher Miller.
In an article about sex scenes in Marie Claire magazine, Kristen Schaal told them she farted on co-star Will Forte during a sex scene. "Carol is aggressively and sexually talking to Phil. That's a lot of diaphragm work, which is also in the danger zone of where the beans are. Finally I just looked at Will and I was like, 'I'm gonna fart on you.' And I did. If you fart on your scene partner it's the most intimate you can get."