Trama

After a high-school girl discovers that she descends from a long line of mutants, she joins other mutants to battle anti-mutants. Ordinary humans that can't run fast get caught in the slaughter.

On her sixteenth birthday, Rin (Yumi Sugimoto), a bullied, timid schoolgirl witnesses her parents killed by fearful, anti-mutant humans. Rins dormant mutant abilities are awakened and she is driven away from her hometown by an angry mob. She meets other mutants called 'Hiruko', and teams up with Rei (Yuko Takayama), a hardarse, rebellious type, and Yoshie (Suzuka Morita), a cute nurse who is conflicted about killing humans. Tak Sakaguchi plays Kasagari, an evil mutant who has an impotent sword growing out of his stomach. Originally trained by Kasagari, the three girls turn against him and his drive to turn Japan into a human-free zone and must fight him and his other loyal mutant minions. In the tradition of 'Machine Girl' and 'Tokyo Gore Police'.—kwedgwood@hotmail.com

Rin (Yumi Sugimoto), a young high school student, is an unassuming and awkward girl who is bullied at school. One day, while being bullied, she feels a sharp pain in her hand. Later, Rin learns that she is a descendant of the ancient Hiruko clan, whose members are mutants gifted with superpowers. No sooner than she learns of this, that her home is raided by anti-Hiruko soldiers. Rin's parents are killed and Rin barely escapes with her life. After killing an entire shopping district out of misunderstanding and grief-fueled rage, Rin meets Rei (Yuko Takayama), another mutant. Rei introduces Rin to a small rag-tag group of mutant rebels led by a transvestite samurai named Kisaragi (Tak Sakaguchi), who is bent on restoring the Hiruko clan's place in the world.

Under the instruction of Kisaragi and Rei, Rin begins training, wearing an iron mask until she can control her powers. While in training, the tentacle-armed Yoshie (Suzuka Morita) tells Rin about Rei's past; only three years ago, Rei had been a freak show attraction at a circus, and the only person to show her compassion and acceptance was a human boy who gave her a gold cross necklace. When the townsfolk killed the boy for loving her, Rei's hatred for humans was born. Rin later finds the necklace after Rei accidentally drops it after a training session.

When Rin achieves control over her powers much sooner than Kisaragi had expected, he orders her, along with Yoshie, to infiltrate an anti-Hiruko conference and attack a high ranking general named Koshimizu. Rin and Yoshie successfully take out Koshimizu, but find themselves unable to kill some innocent surviving humans. Rei, under Kisaragi's orders, kills the survivors.

Eventually, Rin realizes that, in spite of everything that has happened, she cannot turn against her human side. She manages to persuade Yoshie to join in her cause to protect innocent humans rather than kill or subjugate them. Meanwhile, other Hiruko schoolgirls are being brainwashed to carry out suicide bomb attacks at various locations to kill humans. Kisaragi kidnaps and drains the blood of the fervently anti-Hiruko prime minister, which grants him a large grotesque and super-powered body. Yoshie takes on the brainwashed mutant schoolgirls while Rin faces off against Rei. Rin manages to successfully convince Rei to stop her war on humans when she returns Rei's treasured gold cross necklace and triggers fond memories of the human boy who loved her. Rin, Rei and Yoshie team up to defeat Kisaragi and rescue the prime minister.