Patrick Stump of Fall Out Boy sings the introduction song.
Spider-men Peter Parker and Miles Morales are differentiated with the nick-names Spidey and Spin respectively. Gwen Stacy, who is commonly referred to as Spider-Gwen/Spider-woman among comic fans and in Spider-Man: Un nuevo universo (2018) goes by her actual moniker of Ghost-spider.
The first Spider-Man animated series without the involvement of Stan Lee as an executive producer or co-executive producer since El Hombre Araña sin límites (1999).
The words on buildings are not written in English or any real language.