A documentary made up of nine separate segments on the topic of drug addiction. Segments include: "Saturday Night in a Dallas ER," by Jon Alpert; "A Mother's Desperation," by Susan Froemke and Albert Maysles; "The Science of Relapse," by Eugene Jarecki and Susan Froemke; "The Adolescent Addict," by Kate Davis and David Heilbroner; "Brain Imaging," by Liz Garbus and Rory Kennedy; "Opiate Addiction: A New Medication," by D.A. Pennebaker and Chris Hegedus; "Topiramate: A Clinical Trial for Alcoholism," by Alan and Susan Raymond; "Steamfitters Local Union 638," by Barbara Kopple; and "Insurance Woes," by Susan Froemke.
—IMDb editor