- Jackie Estacado: Have you ever loved someone who was so beautiful and pure, you couldn't bear to show them your own darkness?
- Jackie Estacado: I used to know a guy who worked down here. Yeah, Mikey Fat-Lips. Weird son of a bitch. He used to feed his cat subway tokens. One time he asked me to try one, he said they were a good source of iron. Dumb fuck.
- Mobster1: [back turned to the player] Y'know, I'm surprised I've lasted so long doing this. Always figured someone would sneak up behind me in the middle of the night and shoot me in the back.
- Mobster2: Uh-huh...
- Jackie Estacado: I got my first kiss down here. I was fifteen. Some hooker named Candy. She crossed her legs, broke my sunglasses. Good times.
- Crucified: Remember, a powerful enemy now festers within you.
- Uncle Paulie Franchetti: [in a video recording] You've been a pain in the ass since the day I met you Jackie, pissin' and moanin' 'bout the way I do business. Well you need to learn who's calling the shots! I got a surprise for you Jackie- on your birthday! Have a 'blast'!
- Uncle Paulie Franchetti: I loved you like a son Jackie, and you stole from me. You stole my respect and you stole my trust. And when blood takes from blood, someone always pays...
- Cop: Eddie! He's tearin' us apart!
- Capt. Edward 'Eddie' Shrote: Well turn on the fucking lights then! He can't do that shit in the light! And don't *fucking* call me Eddie!
- Capt. Edward 'Eddie' Shrote: Someone get me the power drill.
- Cop: Sure thing Eddie.
- Capt. Edward 'Eddie' Shrote: Don't call me Eddie you fucking moron! It's Captain Shrote!
- Cop: Aw shit! Uh, sure thing Captain Shrote.
- Berserker Darkling: I want to kill someone.
- Gunner Darkling: I am unfamiliar with the concept.
- Gunner Darkling: [attacking an enemy] Maybe not, I guess.
- Jackie Estacado: I've always believed that everyone has a good side, and a bad side. Even a guy like Eddie Shrote. Sure, he's tortured and killed a few people but then again - you should see his bad side. And for what he did to you? Both sides are as good as dead.
- Jimmy the Grape: That fat fucking piece of shit Paulie thinks he can't be touched, right? *Wrong!* Wrong, wrong, wrong *wrong*. He's gonna be touched all right, oh boy is he gonna be touched!
- Jackie Estacado: A job's not worth doing unless you do it right.
- Jackie Estacado: Uncle Paulie's a dead man unless he grows a beard and learns to speak *Swahili*.
- Jackie Estacado: Oh, but he's not going to get the chance. Not for as long as I draw breath.
- Jackie Estacado: I think... What happens when you die? Well, you don't really die. You come to a place like this. Except it doesn't really feel like a place... It feels more like a memory.
- Frank Mortis: Hey man, I wouldn't hang around here if I was you. There's something seriously weird going on here - I'm serious man! I mean, meat shipments come in all the time right, but nothin' ever fucking comes out man! It's probably something illegal, like uh... Rhino meat or somethin' y'know!
- Jackie Estacado: This place reminds me of a guy I knew. Joey Polanco. He had this bad habit of killing the wrong people all the time. Dumbest fucking hitman in history. My Uncle Paulie, threw him under the train down there.
- [You are nothing but my puppet]