Mamie Gummer played the younger version of her real-life mother Meryl Streep, while Natasha Richardson played daughter to her real-life mother Dame Vanessa Redgrave.
Meryl Streep, Toni Collette, Claire Danes, and Dame Eileen Atkins, as well as Executive Producer and Screenwriter Michael Cunningham, worked together on Las horas (2002).
Keira Knightley was considered for the role of young Ann Grant Lord, but she was filming her last scenes of Piratas del Caribe: En el fin del mundo (2007) and finishing the shooting of Expiación, deseo y pecado (2007).
Meryl Streep and Patrick Wilson appeared in Angels in America (2003).