Both Alan Thicke and Joanna Kerns were recently divorced when they were cast for the series; they bonded over this and felt that the bond helped develop their working/on-screen relationship.
About a decade after the original show wrapped, ABC hosted a "Growing Pains" reunion. All the original primary cast was present. During the show, Kirk Cameron admitted that during the run of the original show, he became a born-again Christian and, for a while, became very aggressive with the other cast members and was proselytizing in a very aggressive way. He apologized for this on-air. Joanna Kearns accepted his apology and said, "I'm glad you said that. Because at the time, I was like, 'Stop telling me how to feel!'"
Rival network NBC poked fun at Growing Pains on their show Golden Girls in the episode "Family Affair," with Dorothy claiming, "I can't believe Alan Thicke has a hit series."
When Tracey Gold took her leave of absence during the final season, Carol's absence was explained by an offer to take college courses in London.
Kirk Cameron, Tracey Gold, Jeremy Miller, Joanna Kerns, and Leonardo DiCaprio reunited at Alan Thicke's memorial service in 2016. It was the first time DiCaprio had united with most of the cast since the show's cancellation in 1992.