Bette Davis starred as Mrs. Laura Trent, owner of San Francisco's St. Gregory Hotel. She fell ill and was hospitalized early into the show's first season. Anne Baxter (Davis' nemesis Eve Harrington in La malvada (1950)) took over the hotel as Victoria Cabot, Mrs. Trent's sister-in-law. After Davis recovered, the show's producers asked her to resume her role, but she wasn't happy with the scripts she was sent, so she turned them down.
Heidi Bohay met her husband Michael Spound on the set. They've been married since 1988, and have three sons: Zachary Spound, Jonah Spound, and Gabriel Spound.
Shari Belafonte was cast as Julie Gillette by Aaron Spelling after the role written for her on Los ángeles de Charlie (1976) went to Tanya Roberts.
Henry Mancini's theme for this was a slight re-working of the main theme he wrote for El expreso de Chicago (1976).
Costume Nolan Miller had his hands full working on Dynasty and The Colbys. Nobody on those shows wore the same outfit twice, so Nolan would re-use the costumes for guest stars on Hotel. Nolan only made original costumes for the regular cast (who were mostly in uniform) and special guest stars like Elizabeth Taylor and Eva Gabor. He had designed her costumes on Green Acres.