Ambrosine Phillpotts was no stranger to the Doctor Franchise, she had acted in the film ¡Desvistase, doctor! (1960).
Doctor in Charge was considered the golden era of the Doctor tv franchise. Due to high ratings of the series 1 with 27 episodes, they renewed and had series 2 with 13 episodes.
Barry Evans had the top billing in the Doctor franchise. When he left, Robin Nedwell replaced him and became the main character in this sequel. Ratings spiked when Dr. Warring very comedic actions replaced the comedic yet professional Dr. Upton.