At the time of this short, transcontinental airplane travel was becoming popular. The DC-6, manufactured by Douglas, mentioned here, was one of the planes that dominated the postwar flight boom.
Although the sight of a litter of flying kittens would seem tame, in the '50s, it was quite a bold move. Theoretically, the production code required marriage before babies, even for cats. A few years later, the code would begin to relax, and more previously risqué situations could be shown.
Mel Blanc does not receive his usual screen credit for "voices" on this cartoon, even though he voiced one of the men in the beginning. At this time (1957), Warner Bros. was contractually obligated to give him a screen credit on any cartoon he voiced, even if the role was small. He first received screen credit in the mid-1940s, instead of a raise in salary.
Mel Blanc's fellow voice artist, Daws Butler, provides the narrative in this short.
The flying cat strongly resembles Pussyfoot, seen earlier in Chuck Jones shorts "Feed the Kitty" "Kiss Me Cat" and later in "Cat Feud."