It is unknown who did the voice of the Alpha 60 computer. The voice of Alpha 60 was performed by a man with a mechanical voice box replacing his cancer-damaged larynx who wanted to remain anonymous.
The line by Alpha 60 that begins "Time is the substance of which I am made" is paraphrased from the 1946 essay "A New Refutation of Time" by famous Argentinean writer and fantasist Jorge Luis Borges, which reads: "Our destiny is not frightful by being unreal; it is frightful because it is irreversible and iron-clad. Time is the substance I am made of. Time is a river which sweeps me along, but I am the river; it is a tiger which destroys me, but I am the tiger; it is a fire which consumes me, but I am the fire. The world, unfortunately, is real; I, unfortunately, am Borges."
Several time, Natasha nods her head "No", but says "Yes!" This isn't a mistake. Her character has been programmed in reversed symbolism, where the meaning of words are reversed.
The film's clapperboard is used as the sound of Lemmy's Zippo cigarette lighter closing.
The book that is read and cited in many occasions by Caution and Natascha, _Capitale de la douleur_ (first published in 1926) is actually a poetry work written by the French surrealist author Paul Éluard.