Previous attempts to bring Kraven the Hunter to the big screen had failed. Sam Raimi wanted to include him in Spider-Man 4 before it was canceled, and Kraven's spear was seen in El sorprendente Hombre Araña 2: la amenaza de Electro (2014) as a tease for his planned appearance in the Sinister Six film, which was also canceled. Ryan Coogler wanted to include him in Pantera Negra (2018), taking inspiration from Christopher Priest's Black Panther comic book, but he couldn't secure the rights. Jon Watts wanted Kraven to be the backup villain for Spider-Man: Sin Camino A Casa (2021) in case the multiverse story didn't pan out.
Aaron Taylor-Johnson's six pack abs displayed prominently on the poster are real and not photoshopped. Photographer Gavin Bond who took the original picture confirmed saying, "Yes those abs are real, this young man put in some serious hours at the gym."
In his more human looking form, Rhino wears glasses. In nature, rhinos have terrible eyesight.
Kraven the Hunter was presumably inspired by Richard Connell's 1924 short story "The Most Dangerous Game" about a Russian aristocrat who hunts people for sport. In his debut in "The Amazing Spider-Man" #15 (Aug. 1964), Kraven refers to Spider-Man as "the most dangerous game."
The first Marvel movie from Sony to be released with an "R" rating.