- Described by Kevin James as having "the mouth of a construction worker in the body of a model."
- Quit the Church of Scientology in July 2013 after disputes with its management and questioning leader David Miscavige's rule.
- Her mother is of Ashkenazi Jewish descent (from Austria). Her father's ancestry is Sicilian.
- Has a daughter: Sofia Bella Pagan (b. June 16, 2004) with husband, Angelo Pagán.
- In a 2006 TV Guide /Bravo poll, her The King of Queens (1998) character "Carrie Heffernan" was voted the "hottest housewife" on TV with 31% of the vote narrowly besting characters from Medium (2005), Mi nombre es Earl (2005) and The OC: Vidas Ajenas (2003).
- Moved to Los Angeles with her mother and sister at the age of 13, and left school at 14.
- Younger half-sister, Stephanie, died of cancer in 2013 at the age of 35.
- Auditioned for Courteney Cox's role of "Monica" on Friends (1994). Coincidentally, both actors share the same birthday, but not the same year. (Although she didn't get the role, she later guest-starred in one episode: The One with the Birth (1995).
- Met her husband Angelo Pagán, in 1996 at a Cuban restaurant.
- Close friends with Jennifer Lopez.
- Worked with personal trainer Gina Lombardi to lose 20 pounds for her role in Fired Up (1997).
- Ranked #19 in Stuff magazine's "102 Sexiest Women in the World" (2002).
- Once worked as a telemarketer.
- Her wedding to longtime boyfriend Angelo Pagán was featured in the February 2004 issue of InStyle Magazine.
- Was among the guests at Tom Cruise's and Katie Holmes' wedding ceremony in Italy.
- Loves to sing Karaoke.
- Daughter of Vicki Marshall.
- Her father, George Anthony Remini, died in August 2019.
- Announced engagement to longtime boyfriend Angelo Pagán. (enero de 2003)
- Went back to school to attend NYU.
- Older half-sister of Shannon Farrara.
- Italian descendant.
- Younger sister of Nicole Remini.
- Stepdaughter of George Marshall.
- Friends with Cheryl Burke.
- May 2002: Has joined the nationally syndicated Don and Mike radio show.
- Wore a two-piece Les Habitudes ensemble that included a duchesse satin bustier with silver beads and ivory pearls, and an organza skirt consisting of five layers in her July 2003 wedding to Angelo Pagán.
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