Despite the series being about Natalia Grace, no one on the show actually conferred with Natalia Grace herself.
Christina Hendricks (who plays Cynthia) and Geoffrey Arend (who plays Detective Taylor) were married from 2009-2019.
Despite being in the industry since 1995, this is Ellen Pompeo's 25th role, and 20th when not including playing the same role in other projects and short films.