Guy Clark nació el 6 de noviembre de 1941 en Texas, Estados Unidos. Estuvo casado con Susanna Clark y Susan Spaw. Murió el 17 de mayo de 2016 en Nashville, Tennessee, Estados Unidos.
In the late 1960s, he went to Houston, where he played folk music on a club circuit that included contemporaries Van Zandt and Eric Taylor as well as blues legends Lightnin' Hopkins and Mance Lipscomb. He spent time in San Francisco and Los Angeles which inspired his songs "Madonna w/ Child ca. 1969" and "L.A. Freeway," before moving to Nashville in 1971.