- Worked in California as a steel laborer for six years, until a back injury forced him to look elsewhere. He then studied hairdressing by day at Cerritos College, and took acting classes by night.
- Was a licensed hairstylist.
- He met girlfriend Bo Derek on a blind date in 2002.
- Was a part owner of a club in Seattle called the Fenix Underground.
- Plays guitar and piano.
- Earned a Primetime Emmy Award nomination for playing disc jockey Chris Stevens on Doctor en Alaska (1990).
- Released his debut, self-titled album in April 2006.
- Lives with his girlfriend Bo Derek on a ranch in Santa Ynez, California.
- His father was of English, Irish, Scots-Irish/Northern Irish, and Welsh descent. John's maternal grandfather, Nathan Pavilack, was the son of Russian Jewish immigrants, and John's maternal grandmother, Eldoris Helen Beringo, was from a Lithuanian (Catholic) family. They both moved from Pennsylvania to West Virginia.
- Developed a hunk status as Sarah Jessica Parker's former fiancé, Aidan Shaw, on Sexo en Nueva York (1998), and as Nia Vardalos's suitor, Ian Miller, in the film Mi gran boda griega (2002). He was the only lead in the film to turn down a role in the TV spin-off.
- Resides in Seattle, Washington (2002).
- Is the spokesperson for Applebee's restaurants.
- Due to his commitment to Lucky (2003), he was not able to reprise his Mi gran boda griega (2002) role in the film's spin-off series, My Big Fat Greek Life (2003).
- Good friends with Daryl Hannah.
- Reunited with Nia Vardalos, his Mi gran boda griega (2002) co-star, in Con el amor no hay quien pueda (2009), a romantic comedy that she directed.
- Did a slew of TV commercials in his early years of acting, including a stint as spokesman for Ford Motor Company.
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