Sujay Reu who essays the role of Shri Rama has previously played role of Bharat in Triangle Film Company's show "Siya Ke Ram."
Tarun Khanna's eleventh appearance as Lord Shiva.
Sidhhartha Kumar Tewary, the producer of the show, stated that criticism to film Adipurush, was one of the reason to make the show.
Basant Bhatt who plays Lord Laxman has previously essayed the role of Lord Balaram in Radhakrishna Series.
In an interview, Sidhhartha Kumar Tewary revealed that he especially focused on retaining the musicality of the epic storytelling of the Ramayan. Taking cues from Ramanand Sagar's Ramayan, Shrimad Ramayan features "chaupai" from Tulsidas Ramcharitmanas in almost all of the episodes.