Kevin Feige had only two conditions for the show.
- 1.) The original X-Men - Der Kampf geht weiter (1992) voice-cast had to return.
- 2.) The rights for the theme tune of X-Men - Der Kampf geht weiter (1992) had to be obtained.
This show marks both the first Marvel Studios project with the Marvel Animation banner and Marvel Studios' first X-Men project.
Some of the characters' fight moves are recreated from X-Men: Children of the Atom (1994), X-Men vs. Street Fighter (1996), and the Marvel vs. Capcom video game series by Capcom.
This show marks Cal Dodd and Lenore Zann's first time voicing Wolverine and Rogue in 24 years and George Buza, Alison Sealy-Smith and Adrian Hough's first time voicing Beast, Storm and Nightcrawler in 23 years, since Marvel vs. Capcom 2: New Age of Heroes (2000) for Dodd and Zann and X-Men: Mutant Academy 2 (2001) for Buza, Sealy-Smith and Hough.