This video game takes place in the Normal Timeline of the Pokémon multiverse, together with Pokémon: Feuerrote Edition (2004), Pokémon: Blattgrüne Edition (2004), Pokémon: Smaragd-Edition (2004), Pokémon: Goldene Edition HeartGold (2009), Pokémon: Silberne Edition SoulSilver (2009), Pokémon: Schwarze Edition (2010), Pokémon: Weiße Edition (2010), Pokémon: Schwarze Edition 2 (2012) and Pokémon: Weiße Edition 2 (2012).
First appearance of Looker, member of the international police.
The main frontier brain from Sinnoh battle frontier are Palmer from Battle Tower, Thorton from Battle Factory, Dahlia from Battle Arcade, Darach from Battle Castle and Argenta from Battle Hall.
The main Pokémon legendary on this video game is Giratina.
The new villain member of Team Galactic is Charon.