Pierce Brosnan actually crashed the car in the parking lot and their reactions after the crash were real.
The title is taken from the phrase "Who breaks a butterfly upon a wheel?", meaning taking massive effort in achieving something minor.
"Who breaks a butterfly upon a wheel" is a quotation - sometimes misquoted with "on" in place of "upon" - from Alexander Pope's "Epistle to Dr Arbuthnot" of January 1735. The line has entered common use and has become associated with more recent figures.
This is the second time that Pierce Brosnan and Gerard Butler appeared in a movie together. The first being Der Morgen stirbt nie (1997).
The cartoon being watched in the hotel room is Ed, Edd n Eddy.