- Bill Johnson: It's mating season.
- Cole Burris: What so you're tellin' me there's some snake orgy going on in the jungle?
- Bill Johnson: Yeah, something like that
- Cole Burris: I had this friend, who had this friend who shot documentaries, and he and his whole crew went down to the Amazon, and they were all eaten by snakes, and thats a true story
- Gordon Mitchell: Come on Cole, you knew a guy who knew a guy. That's an urban myth.
- [last lines]
- Gail Stern: So how much further to my bath?
- Bill Johnson: Kotabaru? I'd say... another day downriver.
- Cole Burris: Another day? I'm not rowing another day, homeboy.
- Bill Johnson: All right. Let's see, we got this shortcut right up -
- Sam Rogers, Cole Burris, Gail Stern: No!
- Gail Stern: [seeing Bill's boat for the first time] I've seen subway carts in better shape than this!
- Dr. Ben Douglas: [the expedition is wading through a marsh - Ben starts humming the theme from "Jaws"] Duuh, dum, duuh, dum. Dum dum dum dum dum dum...
- Gail Stern: Stop that, or I swear to God I'll kill you!
- [Ben gets pulled under the water]
- Gordon Mitchell: Are you okay now?
- Gail Stern: Yeah, I'm fine. And keep your hands off of me!
- Gordon Mitchell: It might be hard, but I'll try!
- Gail Stern: Can you hear me now? Shit. Can you hear me now? Can you hear me now?
- Cole Burris: WE can!
- Gail Stern: Can you hear me now?
- [Gail plunges into the river]
- Gordon Mitchell: Hey Gail, can you hear me now?
- Sam Rogers: We're in the middle of the jungle Jack, at this point your authority is what we say it is.
- [after Sam decapitates an anaconda]
- Cole Burris: That's what I'm talking about! That's what I'm talking about, Sam! Oh, my God! You're the bomb! You Lorena Bobbitt-ed that ass!
- [to the dead decapitated anaconda]
- Cole Burris: How you like that, bitch? She sliced you! Diced you! She cut you up! That was like Sam with the samurai action! Say it now...
- [another anaconda snatches up Cole]