Val Kilmer prepared for his role by studying with a sculptor friend of his in New Mexico who had lost his sight in Vietnam. At 49:30 (NTSC) he is admiring a sculpture when he first visit's Amy's flat.
There have been several references to Val Kilmer in Friends (1994), with the most notable being when Ross rented Kilmer's jacket that he wore to the premiere of this movie.
Val Kilmer had a reputation for being difficult to work with clashing with many actors and directors. However Mira Sorvino said she loved working with him on this film and found him incredibly easy to work with.
Cast member Drena De Niro is the daughter of Robert De Niro, who also played a fictionalized patient of Oliver Sacks in Zeit des Erwachens (1990).