The first Broadway run of The Indestructible Wife by Frederic Hatton and Fanny Hatton took place in January and February, 1918, at the Hudson Theatre and ran for twenty-two performances. The production's cast consisted of Lionel Atwill, Roland Byram, Clay Clement, John Cromwell, Fred Esmelton, Minna Gombell, Jane Houston, Esther Howard, Howard Kyle, Edward Le Duc, Mrs. Jacques Martin and Irene Timmons. William A. Brady produced the show.
According to the American Silent Feature Film Database, a fragment of this film is in the BFI/National Film And Television Archive (London).