- Had a long-time involvement with but never married Don Henley of the Eagles. In fact, her first marriage did not occur, until she was in her late 50s, with noted philanthropist and Wall Street broker, Richard Gilder.
- Professor at University of Houston, Houston Texas (März 2005)
- She is very active in raising money for the research and prevention of non-Hodgkin lymphoma, particularly because her brother's life was taken by same.
- Her younger brother, with whom she was extremely close, tragically died of Non-Hodgkin's lymphoma in 1978. She made a choice to take a three-year hiatus from acting as a result just as her career had reached its peak. Her film career never fully recovered after she came back. She originally was offered the top Bondian love interest that Barbara Bach portrayed in Der Spion, der mich liebte (1977) by director Lewis Gilbert but turned it down because of her initial self-imposed hiatus. The director, however, convinced her to play Holly Goodhead in Moonraker - Streng geheim (1979) before she left the screen.
- Was the original choice for Agent Triple X (Anya Amasova) in Der Spion, der mich liebte (1977), but as a moment of fate, got her chance as the 007 girl in Moonraker - Streng geheim (1979) after Lewis Gilbert sat next to her on an airline flight.
- Battled breast cancer in 2005.
- Before entering films, she was one of the very top models of the 1970s.
- Was the daughter of Barbara Wayne (née Kirkland) and Marion Clay Chiles, who was the brother of oil tycoon and Texas Rangers owner Eddie Chiles.
- She was flying back to America having completed filming Tod auf dem Nil (1978) and found herself sitting next to director Lewis Gilbert who was looking for an actress to play Holly Goodhead in the film Moonraker - Streng geheim (1979), and asked her to audition for him.
- Attended prestigious Finch College where she was discovered by a Glamour magazine editor and that led to her fashion modeling career.
- Was diagnosed with breast cancer in 2001, not long after the death of her father M. Clay Chiles (brother of oil tycoon Eddie Chiles).
- Graduate of the University of Texas, Austin in 1969.
- Her husband Richard Gilder donated money to a school called Northfield Mount Hermon, which is located at Mount Hermon in Massachusetts, so the school decided to name their theater the Chiles Theater after her.
- Has homes in both New York and Houston.
- First attended the University of Texas at Austin before continuing her studies at the prestigious Finch College in New York City, where she was discovered for modeling by Glamour magazine and eventually joined the Wilhelmina company as a haute couture model.
- José Ferrer directed her on stage in productions of "Cat on a Hot Tin Roof" and "The Best Man" in the mid 1980s.
- Directed by four Academy Award winners: Sydney Pollack, James L. Brooks, Cameron Crowe, and Quentin Tarantino.
- On the popular prime time soap Dallas (1978), she played Holly Harwood, a young woman who inherits her late father's oil company. She has a real life connection to the oil industry as her paternal uncle was oil tycoon Eddie Chiles.
- In 1982, she starred on the popular drama Dallas (1978) for one year, alongside Ken Kercheval. 10 years later, they played husband and wife on an episode of In der Hitze der Nacht (1988).
- Took acting lessons from a number of prominent drama teachers: Roy London, Milton Katselas, José Quintero, and Sanford Meisner.
- Last surviving main cast member of moonraker. Richard Kiel(Jaws) died 2013, Roger Moore(James Bond) died 2017, Michael Lonsdale (Hugo Drax) died 2020.
- Her last name is pronounced like "files" with a "ch".
- Stepmother of Ginny Gilder.
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