- Made his directorial debut with "Per Grazia Ricevuta" (1971), which won the Best First Film award at Cannes.
- He has a natural daughter, Tonina (b.1985), from a relationship with a Bulgarian woman.
- Wanted to work with Federico Fellini. He complained to Fellini that he never called him and that he wanted to work with him just once. Just one scene, half a scene, and that he'd do it without pay. Fellini replied, "You have too much personality!".
- Popular Italian leading man, equally adept at drama and comedy.
- Buried in the Verano Cemetery in Rome in its family grave. It is placed in the same square of Marcello Mastroianni.
- Started in 1949 as a voice-over actor, for example, dubbing French star Gerard Philippe into Italian.
- A former law student, he made a name for himself in the world of Italian show business as a radio and music hall performer in the World War II years.
- Father of Giovanna, Roberta Manfredi and Luca Manfredi. Grandfather of Francesco, Matilde and Margherita Manfredi (Luca's children) and of Sarah Masten, Matteo Simone and Leonardo Simone (Roberta's children).
- Father-in-law of Alberto Simone. Former father-in-law of Nancy Brilli and Werner Masten (Roberta's first husband).
- He refused the role of Don Ameche in David Mamet 's "Thing Change".
- He's portrayed by Elio Germano in In arte Nino (2016).
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