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Eva is a young agent in the robbery bureau of the Catalan Police Department who is recruited to hunt down a serial who has been murdering old ladies. The young agent, a single mother of a six-year-old boy, must reconcile the capture of the killer with her obligations as a mother, while at the same time confronting Chief Inspector Xavier Vidal, the man who had always barred her from entering the homicide bureau.

The Galician fisherman Ramón Sampedro is left a quadriplegic following a diving accident. He finds that there is no dignity in his life and wants to end his life. Not being able to do this without assistance, he starts to fight for the right to die.